RESEARCH FACULTY
高采月
特聘副研究员 · 硕士生导师
干燥病与 T 细胞免疫
- 身份
- 科研骨干
- 研究方向
- 干燥病与 T 细胞免疫
PROFILE
个人简介
特聘副研究员，硕士生导师。
主要从事自身免疫性疾病的免疫学发病机制及调控研究，重点探究 T 细胞在多种自身免疫性疾病中的特征、功能及与组织微环境的交流。相关工作发表在 JCI Insight、Arthritis & Rheumatology、Clinical Reviews in Allergy & Immunology 等期刊。
RESEARCH
研究方向
- 干燥病与 T 细胞免疫
SELECTED PAPERS
代表性论文
- Single-cell profiling reveals clonal CD8+ T cell-derived IFNγ drives Sjögren's disease-related dacryoadenitisHao-Xian Zhu#, Fang-Fang Li#, Xiao-Min Chen, Bing-Yang Zhang, Ting Xu, Zhe-Xiong Lian*, Cai-Yue Gao* & Qian-Li Meng*
- Identification of pathogenic PD-1+CD8+ T cells for effective chimeric antigen receptor therapy in a murine model of Sjögren's diseaseJin-Fen Ma#; Ting Xu#; Hao-Xian Zhu#; Xiao-Min Chen; Liang Li; Zhi-Bin Zhao; Liwei Lu; Yang Li*; Zhe-Xiong Lian*; Cai-Yue Gao*站内成果页 →
- Single-cell profiling reveals pathogenic role and differentiation trajectory of granzyme K+CD8+ T cells in primary Sjögren's syndromeTing Xu#, Hao-Xian Zhu#, Xing You#, Jin-Fen Ma, Xin Li, Pan-Yue Luo, Yang Li*, Zhe-Xiong Lian*, and Cai-Yue Gao*站内成果页 →
- Tissue-Resident Memory CD8+ T Cells Acting as Mediators of Salivary Gland Damage in a Murine Model of Sjogren's SyndromeCai-Yue Gao, Yuan Yao, Liang Li, Shu-Han Yang, Hui Chu, Koichi Tsuneyama, Xiao-Mei Li*, M. Eric Gershwin, Zhe-Xiong Lian*
- Immunobiology of T cells in Sjögren's syndromeYuan Yao#, Jin-Fen Ma#, Christopher Chang, Ting Xu, Cai-Yue Gao*, M. Eric Gershwin, Zhe-Xiong Lian*
- Multi-Omics Profiling Identities Pathways Associated With CD8+ T-Cell Activation in Severe Aplastic AnemiaXing You#, Qiong Yang#, Kai Yan, Song-Rong Wang, Rong-Rong Huang, Shun-Qing Wang, Cai-Yue Gao*, Liang Li* and Zhe-Xiong Lian*
- Increased proportion of follicular helper T cells is associated with B cell activation and disease severity in IgA nephropathyDu W#, Gao CY#, You X, Li L, Zhao ZB, Fang M, Ye Z, Si M, Lian ZX, Yu X*